Visualización y uso de técnicas de Aprendizaje Máquina Supervisado para la predicción de resultados de la Fórmula 1

[Resumen] La Fórmula 1 es considerada como la competición más prestigiosa y tecnológica en el mundo del automovilismo, donde diferentes equipos y sus pilotos compiten por ganar carreras y conseguir el campeonato. Con el uso de datos históricos de carreras previas y mediante la aplicación de modelos de predicción basados en Aprendizaje Máquina Supervisado se pueden predecir los resultados de las siguientes carreras. Este proyecto tiene como objetivo investigar la predicción de los ganadores de los campeonatos, tanto de pilotos como de constructores, proponiendo diversos algoritmos y siguiendo una metodología de minería de datos. Se presentan una serie de visualizaciones que ayudan a comprender las diferentes variables del conjunto de datos y la historia reciente del deporte. Mediante un preprocesado de los datos y diversas pruebas con los algoritmos propuestos, se consiguieron unos resultados muy alentadores para la predicción de ambos campeonatos. El modelo que mejores resultados obtuvo fue la Red Neuronal Artificial, seguida de cerca por la Regresión por Vector de Soporte y los métodos basados en árboles.[Abstract] Formula 1 is considered to be the most prestigious and technological competition in the world of motorsport, where different teams and their drivers compete to win races and achieve the championship. By using historical data from previous races and applying prediction models based on Supervised Learning, it is possible to predict the results of the following races. This project aims to investigate the prediction of the championship winners, both drivers and constructors, by proposing different algorithms and following a data mining methodology. A series of visualizations are presented to help understand the different variables of the dataset and the recent history of the sport. By preprocessing the data and testing the proposed algorithms, very encouraging results were achieved for the prediction of both championships. The best performing model was the Artificial Neural Network, closely followed by the Support Vector Regression and tree-based methods.Traballo fin de grao (UDC.FIC). Ciencia e enxeñaría de datos. Curso 2022/202

GLEAM v3 : satellite-based land evaporation and root-zone soil moisture

The Global Land Evaporation Amsterdam Model (GLEAM) is a set of algorithms dedicated to the estimation of terrestrial evaporation and root-zone soil moisture from satellite data. Ever since its development in 2011, the model has been regularly revised, aiming at the optimal incorporation of new satellite-observed geophysical variables, and improving the representation of physical processes. In this study, the next version of this model (v3) is presented. Key changes relative to the previous version include (1) a revised formulation of the evaporative stress, (2) an optimized drainage algorithm, and (3) a new soil moisture data assimilation system. GLEAM v3 is used to produce three new data sets of terrestrial evaporation and root-zone soil moisture, including a 36-year data set spanning 1980-2015, referred to as v3a (based on satellite-observed soil moisture, vegetation optical depth and snow-water equivalent, reanalysis air temperature and radiation, and a multi-source precipitation product), and two satellite-based data sets. The latter share most of their forcing, except for the vegetation optical depth and soil moisture, which are based on observations from different passive and active C-and L-band microwave sensors (European Space Agency Climate Change Initiative, ESA CCI) for the v3b data set (spanning 2003-2015) and observations from the Soil Moisture and Ocean Salinity (SMOS) satellite in the v3c data set (spanning 2011-2015). Here, these three data sets are described in detail, compared against analogous data sets generated using the previous version of GLEAM (v2), and validated against measurements from 91 eddy-covariance towers and 2325 soil moisture sensors across a broad range of ecosystems. Results indicate that the quality of the v3 soil moisture is consistently better than the one from v2: average correlations against in situ surface soil moisture measurements increase from 0.61 to 0.64 in the case of the v3a data set and the representation of soil moisture in the second layer improves as well, with correlations increasing from 0.47 to 0.53. Similar improvements are observed for the v3b and c data sets. Despite regional differences, the quality of the evaporation fluxes remains overall similar to the one obtained using the previous version of GLEAM, with average correlations against eddy-covariance measurements ranging between 0.78 and 0.81 for the different data sets. These global data sets of terrestrial evaporation and root-zone soil moisture are now openly available at www.GLEAM.eu and may be used for large-scale hydrological applications, climate studies, or research on land-atmosphere feedbacks

Is the biocompatibility of copper with polymerized natural coating dependent on the potential selected for the electropolymerization process?

With the intention of taking care of the environment and human health, the development of alternative eco-friendly methods to inhibit metal corrosion is intensively encouraged. In previous works we showed that some phytocompounds components of essential oils such as carvacrol (Carv) and thymol (TOH) are able to be electropolymerized on metals and they seem to be promissory for this purpose. The aim this paper is to investigate if the biocompatibility of copper covered by coatings formed by electropolymerization of Carv and TOH (polyCarv and polyTOH) is related with the potential selected for the electropolymerization process. Potentiostatic perturbations at different potentials, AFM images, ATR-FTIR spectroscopy and measurements of copper ions release provided suitable information to make a detailed analysis of different stages of the electropolymerization process that leads to polyCarv and polyTOH layers on copper surface. The change of the characteristics of the coatings over time was evaluated after several polymerization periods and current transients were interpreted by using nucleation and growth models. Results showed interesting changes in the polymerization process with the electrochemical perturbation, nature of the isomer, and time of the treatment. The treatment that provides the most protective, transparent and homogeneous layer, that strongly increased the biocompatibility of Cu could be selected: electropolymerization of Carv at 0.4 V. Results highlight the importance of the detailed study of the evolution of the electropolymerization processes to select the best ecofriendly condition due the high impact of potential perturbation and polarization time on the biocompatibility of the resulting polymeric layer-copper system.Facultad de IngenieríaInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicada

p38MAPK and Chemotherapy: We always need to hear both Sides of the Story

The p38MAPK signaling pathway was initially described as a stress response mechanism. In fact, during previous decades, it was considered a pathway with little interest in oncology especially in comparison with other MAPKs such as ERK1/2, known to be target of oncogenes like Ras. However, its involvement in apoptotic cell death phenomena makes this signaling pathway more attractive for many cancer research laboratories. This apoptotic role allows to establish a link between p38MAPK and regular chemotherapeutic agents such as Cisplatin or base analogs (Cytarabine, Gemcitabine or 5-Fluorouracil) which are currently used in hospitals across the world. In fact, and more recently, p38MAPK has also been connected with targeted therapies like tyrosine kinase inhibitors (vg. Imatinib, Sorafenib) and, to a lesser extent, with monoclonal antibodies. In addition, the oncogenic or tumor suppressor potential of this signaling pathway has aroused the interest of the scientific community in evaluating p38MAPK as a novel target for cancer therapy. In this review, we will summarize the role of p38MAPK in chemotherapy as well as the potential that p38MAPK inhibition can bring to cancer therapy. All the evidences suggest that p38MAPK could be a double-edged sword and that the search for the most appropriate candidate patients, depending on their pathology and treatment, will lead to a more rational use of this new therapeutic tool

Determination of lithic raw materials in Cantabrian Spain during Greenland Stadial 2: The Magdalenian of Tito Bustillo Cave (Ribadesella, Asturias)

The lithic assemblage studied here comes from the space known as the ' Area de Estancia in Tito Bustillo Cave (Ribadesella, Asturias, Spain), a representative Magdalenian site. The remains were found in Sub-level 1c2 in the Lower Complex (1LC), which was excavated by J.A. Moure Romanillo from 1981 to 1983 and is associated with abundant evidence of osseous industry, fauna, portable art, etc. The present study is especially innovative because it introduces a holistic approach to the understanding of the management of lithic resources by hunter -gatherer groups in the late Pleistocene. It establishes the two main groups of raw materials in the assemblage (flint and quartzite) and the different types through a petrographic description, and the different procurement strategies that were employed. Some preliminary results about the functionality of these tools are also offered. The occupants of this cave during the Greenland Stadial 2 traced a diversified and complex dynamic of exploitation of lithic resources that combined both the most immediate, easily available and in greater volume (for example, quartzite and Pilon similar to a flint), and the most distant, of good knapping quality (Flysch flint, funda-mentally). This circulation of raw materials is parallel to the patterns detected in other deposits in the region with a similar chronology. Significant differences are observed in the knapping schemes between raw materials based on the production of blanks for the manufacture of tools, whose typological classification and analysis of use-wear makes us propose a specialized and little diversified functionality, which is usually related to that of temporary occupations.This research was undertaken in the context of Ph.D. scholarship Junta de Castilla y León and Fondo Social Europeo (S. Martín-Jarque), and of the Spanish projects PID2020-114462 GB-100 and PID2020-118359 GB-I00 both funded by the Programa Estatal de Fomento de Generación de Conocimiento y Fortalecimiento Científico y Tecnológico, of the Spanish Ministry of Science and Innovation. A. Prieto is a postdoctoral researcher supported by the UPV/EHU and the Spanish Ministry of Science with UE-Next-Generation funds (María Zambrano Fellowship). His research was also supported by the PID2021-126937NB-I00 and the HAR2017-82493-C3-1-P Spanish Ministry of Science projects

Integrative Transcriptome, Genome and Quantitative Trait Loci Resources Identify Single Nucleotide Polymorphisms in Candidate Genes for Growth Traits in Turbot

Growth traits represent a main goal in aquaculture breeding programs and may be related to adaptive variation in wild fisheries. Integrating quantitative trait loci (QTL) mapping and next generation sequencing can greatly help to identify variation in candidate genes, which can result in marker-assisted selection and better genetic structure information. Turbot is a commercially important flatfish in Europe and China, with available genomic information on QTLs and genome mapping. Muscle and liver RNA-seq from 18 individuals was carried out to obtain gene sequences and markers functionally related to growth, resulting in a total of 20,447 genes and 85,344 single nucleotide polymorphisms (SNPs). Many growth-related genes and SNPs were identified and placed in the turbot genome and genetic map to explore their co-localization with growth-QTL markers. Forty-five SNPs on growth-related genes were selected based on QTL co-localization and relevant function for growth traits. Forty-three SNPs were technically feasible and validated in a wild Atlantic population, where 91% were polymorphic. The integration of functional and structural genomic resources in turbot provides a practical approach for QTL mining in this species. Validated SNPs represent a useful set of growth-related gene markers for future association, functional and population studies in this flatfish speciesThis work was funded by Spanish Ministry of Economy and Competitiveness and European Regional Development Funds (AGL2012-35904), and Ministry of Science and Innovation (Consolider Ingenio, Aquagenomics, CSD200700002). DR was supported by a FPU fellowship funded by Spanish Ministry of Education, Culture and Sport. Thanks to Lucía Ínsua for technical assistance. We thank the High-Throughput Genomics Group at the Wellcome Trust Centre for Human Genetics for the generation of the sequencing data, and the Spanish National Genotyping Center (CEGEN-ISCIII)-USC node for SNP genotyping support. We acknowledge the support of the Centro de Supercomputación de Galicia (CESGA) in the completion of this workS

Diseño e implementación de un huerto universitario ecológico como recurso didáctico para futuros maestros de Educación Primaria e Infantil (Campus Viriato, Zamora)

Memoria ID-0045. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2016-2017

Preparation of marine silage of swordfish, ray and shark visceral waste by lactic acid bacteria

The goal of the present work was to study the efficacy of several lactic acid bacteria (LAB) as bio-silage inoculants of swordfish, ray and shark viscera by-products. A sterilised medium was initially used as a model system for assessing the potential of these microorganisms in batch and fed-batch cultures with re-neutralisation. In all cases, batch cultivations without re-neutralisation led to the highest production and yields of the main metabolites of LAB fermentation (lactic and acetic acids). The dynamics of these metabolites followed a conversion pattern from lactic to acetic acid with a final joint concentration over 16 g/L and final pH lower than 4.5. Both productions were modelled by means of logistic modified equations. In addition, the capability of LAB to ferment the fish visceral wastes was always high and easily reproducible. Finally, the results obtained for non-sterilised fermentations with Lactobacillus casei CECT 4043 were similar to those obtained for sterilised media, and a stable material was obtained after 72 h of culture.Peer reviewe

Coronavirus fear of contagion and compliance with social distancing measures: evidence for a sample of a Spanish university community

Background. Social distancing measures have been one of the core pillars of the strategy against COVID-19 in all the countries. This study aims at understanding what motivates behaviours and compliance with social distancing measures among students and workers from a Spanish public university. Methods. We carry out two logistics models considering two different dependent variables: not maintaining social relation with non-cohabiting people and not to leave home except for emergencies (n = 507, sample is formed by students and workers from the University of Cantabria in the North of Spain). Results. Being very concerned about getting ill suggests higher risk of not maintaining social relation with non-cohabiting people. Getting older increase the probability of not leaving home except for emergencies as happens with those who are very concerned about getting ill. Young people often living with vulnerable older relatives may affect students' behaviour. Conclusions. Our findings suggest that compliance with social distancing measures depends on several factors related to age, the number or kind of cohabiting people and level of concern about getting ill. Policies should address all these factors through a multidisciplinary perspective

The Escalada Formation: Characterization of a potential chert supply source in the Cantabrian Mountains (NW Spain) during prehistory.

A study of the chert nodules found in the Escalada Formation (Carboniferous, Ponga region, Cantabrian Zone) was carried out as a means to characterise a number of lithic raw materials found in several prehistoric sites of the Cantabrian Mountains (NW Spain). This study comprises fieldwork aimed at locating the outcrops and obtaining samples. Some selected samples from two localities were used for both petrological (macroscopic and microscopic analyses from thin sections) and geochemical (X-ray fluorescence and powder diffraction) analysis. The macroscopic study shows a rather homogeneus coloration and a conchoidal fracture although two extreme types of cherts with a variety of intermediate forms can be differentiated according to the matrix composition. The microscopic analysis shows a high heterogeneity in carbonate versus silica percentage and gentle differences in some other features such as type of silica, origin of carbonates, occurrence of organic matter and type of skeletal components. The results of several geochemical analysis suggest that there are not geochemical features neither in the major elements nor in the traces that allows us to clearly distinguish between the analysed samples. All these studies allow us to define the main features of these chert nodules and to establish several types and varieties among them. Those varieties with high percentage of silica and with a more homogeneous matrix are the most suitable samples for knapping. These results together with the study of the geological and geographical location of archaeological sites suggest that the nodules from the Escalada Formation likely were lithic material supply sources used in knapping activitiesWhen aiming to demonstrate the use of these materials at archaeological sites the sole macroscopic analysis of the pieces does not suffice; further analyses, such as those involving thin sections, are necessary. The absence of chert from Escalada Formation in some Mesolithic sites in the area was confirmed via these additional analyses